The Transnational Access 1 (TNA1) "Cross platform screening and optimization service“ and the corresponding Joint Research Activity (JRA1) "Improved optimization and harmonization of cross-vector screening“ will combine the expertise of six different partners (IME, SSI, UOXF, iBET, BPRC and UNISI) to provide the unique offer to test vaccine candidates in a comprehensive range of different expression hosts, to identify the optimal production system for further pre-clinical and clinical development. The development of SOPs and the implementation of standardized procedures wherever possible will enable the generation of reliable data on protein yields and quality to provide valid decision criteria on the choice of expression system. Within the "European Training Programme in Vaccinology“ Fraunhofer IME will provide two-day Training Modules focusing on three different topics. The module “Assay Development and Validation” will provide an insight into “state of the art” applications of SPR-technology in the context of vaccine development. Besides the detailed analysis of antibody responses, the training will address the development and validation of quality control and quantification assays. The training module “Process Development and scale up”, will give a deeper insight into the topic by discussing “real life” scenarios. Based on the experiences with several GMP-production processes, the module “Requirements for GMP-production” will improve the perception of essential prerequisites that have to be taken into account before heading for the “GMP” adventure.